Repaglinidum [Inn-Latin]

• Hypoglycemic Agents
• Meglitinides
• ATC:A10BX02

• AG-EE 388 ZW
• AG-EE 623 ZW
• Prandin
• Repaglinida [Inn-Spanish]
• Repaglinide [Usan]
• Repaglinidum [Inn-Latin]

No information avaliable

C₂₇H₃₆N₂O₄

http://www.rxlist.com/cgi/generic/prandin.htm

Repaglinidum_[Inn-Latin] FDA

Repaglinidum_[Inn-Latin] MSDS

W. Grell et al. Int. PCT. pat. Appl. WO 93 00337

452.586 g/mol

130-131 ^oC

Nessuna informazione disponibile

Solid

5.798

Compressa

Per il trattamento del diabete mellito di tipo II.

La repaglinide è un orale di glucosio nel sangue farmaco che riduce della classe meglitinide utilizzato nella gestione del diabete di tipo 2 (noto anche come diabete non insulino-dipendente o NIDDM mellito). Repaglinide abbassa i livelli di glucosio nel sangue stimolando il rilascio di insulina dal pancreas. Questa azione è dipende dal funzionamento delle cellule beta nelle isole pancreatiche. Rilascio di insulina glucosio-dipendente è e diminuisce a basse concentrazioni di glucosio.

Rapido (biodisponibilità è del 56%)

LD50> 1 g / kg (ratto) (W. Grell)

PATIENT INFORMATION

Patients should be informed of the potential risks and advantages of Repaglinide (PRANDIN) and of alternative modes of therapy. They should also be informed about the importance of adherence to dietary instructions, of a regular exercise program, and of regular testing of blood glucose and HbA1c. The risks of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development and concomitant administration of other glucose-lowering drugs should be explained to patients and responsible family members. Primary and secondary failure should also be explained.

Patients should be instructed to take Repaglinide before meals (2, 3, or 4 times a day preprandially). Doses are usually taken within 15 minutes of the meal but time may vary from immediately preceding the meal to as long as 30 minutes before the meal. Patients who skip a meal (or add an extra meal) should be instructed to skip (or add) a dose for that meal.

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